The USA Eagles face Tonga in Spain on Saturday with Langilangi Haupeakui and Sila Puafisi both on the bench for their respective countries.
Simone Favaro was on the losing side for Italy against the All Blacks last weekend and will be hoping for better fortunes in Florence this Saturday as the South Africa visit.
In Bucharest, Djustice Sears-Duru starts on the bench for Canada as they take on the Romanians.
Saturday 19 November
Italy v South Africa (Florence 2pm)
Tonga v USA (San Sebastian)
Romania v Canada (Bucharest)