Thom's inclusion is one of three changes to the starting line-up that battled to a 9-8 win over Australia.
Thom comes in on the left wing in place of Simon Danielli with Alex Grove shuffling along to inside centre with Graeme Morrison dropping out. Ben Cairns comes in at outside centre.
John Barclay earns a well-deserved rest after Saturday's heroics with Alan MacDonald winning his first cap.
Chris Cusiter has recovered from a head knock and continues as skipper.
Scotland
15 Rory Lamont (Toulon)
14 Sean Lamont (Scarlets)
13 Ben Cairns (Edinburgh)
12 Alex Grove (Worcester Warriors)
11 Thom Evans (Glasgow Warriors)
10 Phil Godman (Edinburgh)
9 Chris Cusiter (Glasgow Warriors) CAPTAIN
1 Allan Jacobsen (Edinburgh)
2 Ross Ford (Edinburgh)
3 Moray Low (Glasgow Warriors)
4 Nathan Hines (Leinster)
5 Alastair Kellock (Glasgow Warriors)
6 Alasdair Strokosch (Gloucester)
7 Alan MacDonald (Edinburgh) *
8 Johnnie Beattie (Glasgow Warriors)
Substitutes
16 Dougie Hall (Glasgow Warriors)
17 Kyle Traynor (Edinburgh)
18 Jason White (Clermont Auvergne)
19 Richie Vernon (Glasgow Warriors)
20 Rory Lawson (Gloucester)
21 Chris Paterson (Edinburgh)
22 Nick De Luca (Edinburgh)
*= New cap