Full back Kyle Rowe and inside centre Sione Tuipulotu retain their places in the 15 and 12 jerseys respectively.
Tuipulotu also continues as co-captain.
Kyle Steyn moves from to outside centre - while retaining the vice-captaincy - and he is replaced at wing by club mate, Jamie Dobie.
Prop Nathan McBeth and flanker Gregor Brown are in line to win their second international caps having been selected to start on Saturday.
Another four Warriors are on the bench - Max Williamson, Rory Darge, Adam Hastings and Stafford McDowall.
Scotland
15 Kyle Rowe - Glasgow Warriors (5)
14 Jamie Dobie - Glasgow Warriors (4)
13 Kyle Steyn - Vice-Captain - Glasgow Warriors (21)
12 Sione Tuipulotu - Co-Captain - Glasgow Warriors (26)
11 Arron Reed - Sale Sharks (1)
10 Ben Healy - Edinburgh Rugby (6)
9 Gus Warr - Sale Sharks (1)
1 Nathan McBeth - Glasgow Warriors (1)
2 Dylan Richardson - Sharks (2)
3 Will Hurd - Leicester Tigers (1)
4 Alex Craig - Scarlets (3)
5 Ewan Johnson - Oyonnax (1)
6 Gregor Brown - Glasgow Warriors (1)
7 Jamie Ritchie - Co-Captain - Edinburgh Rugby (50)
8 Josh Bayliss - Bath Rugby (6)
Substitutes
16 Patrick Harrison - Edinburgh Rugby (uncapped)
17 Pierre Schoeman - Edinburgh Rugby (32)
18 Javan Sebastian - Edinburgh Rugby (8)
19 Max Williamson - Glasgow Warriors (2)
20 Rory Darge - Glasgow Warriors (20)
21 Adam Hastings - Glasgow Warriors (28)
22 Stafford McDowall - Glasgow Warriors (3)
23 Matt Currie - Edinburgh Rugby (2)